目的 提高对儿童敌草快中毒的临床特征的认识。方法 回顾性分析我院收治的8例敌草快中毒儿童的临床资料。分别以“敌草快中毒”和“diquat”“diquat poisoning”为关键词检索中国知网、万方数据库、PubMed数据库，检索时间为建库至2024年4月，查阅既往病例文献进行汇总分析。结果 本研究8例患儿中男2例，女6例，年龄3~14岁，服毒量1~180 g，其中6例出现消化系统症状，4例出现不同程度肺损伤，2例出现较严重的神经系统症状，给予洗胃、补液、血液净化等治疗，最终6例存活，2例死亡（25%）。文献复习共纳入16例病例，9例出现不同程度肺损伤，国内报道病例12例均存活，国外报道病例4例及本研究2例死亡病例均较早出现严重神经系统症状。结论 儿童轻中度DQ中毒引起的肺损伤是可逆的，但重度DQ中毒会进展迅速导致多脏器功能衰竭，尤其是早期出现严重神经系统症状者多预后不良。

Objective To enhance the understanding of the clinical characteristics of diquat poisoning in children. Methods A retrospective analysis was conducted on the clinical data of eight pediatric patients diagnosed with diquat poisoning at our hospital. "Diquat" and "diquat poisoning" were used as keywords to search in CNKI, Wanfang and PubMed database from inception to April 2024. Previous case reports were reviewed and summarized. Results Among the eight cases, there were two males and six females aged 3-14 years who ingested 1-180 g of poison. Six cases exhibited gastrointestinal symptoms, four cases showed varying degrees of lung injury, and two cases presented with severe neurological symptoms. The patients received gastric lavage, rehydration, and blood purification therapy. Ultimately, six patients survived, while two (25%) died. Additionally, sixteen cases from nine published papers were analyzed, revealing that nine cases developed different degrees of lung injury. All twelve cases reported in China survived, whereas four cases reported internationally and the two fatalities in this study exhibited earlier-onset severe neurological symptoms. Conclusion Lung injury caused by mild-to-moderate diquat poisoning in children is reversible, but severe diquat poisoning can progress rapidly and lead to multiple organ failure. Patients presenting with early severe neurological symptoms generally have a poor prognosis.