儿童急性胰腺炎（AP）发病率呈逐年上升趋势。目前儿童重症急性坏死性胰腺炎尚欠缺规范而标准的诊疗方案，临床工作中多借鉴和参考成人标准。药物的持续区域动脉灌注已在成人早期急性坏死性胰腺炎的治疗中被应用，但儿童AP的病因、病理生理过程及药代动力学不同于成人且存在一定的个体差异，针对儿童AP的相关报道甚少。文章报道了1例儿童重症急性坏死性胰腺炎通过持续区域动脉灌注治疗，由留置导管将药物注入指定部位的案例，并就儿童AP中持续区域动脉灌注治疗的适用性进行了探讨，以期促进儿童AP诊治的进步。

The incidence of acute pancreatitis (AP) in children has shown a yearly increasing trend. Currently, standardized and definitive diagnosis and treatment protocols for severe acute necrotizing pancreatitis in children are lacking, and clinical practice often relies on adapting adult guidelines. Continuous regional arterial infusion of medication has been applied in the treatment of early-stage acute necrotizing pancreatitis in adults. However, the etiology, pathophysiological processes, and pharmacokinetics of AP differ in children compared to adults, with certain individual variations also present. Consequently, reports on its application specifically in children with AP are scarce. This article presents a case of severe acute necrotizing pancreatitis in a child treated via continuous regional arterial infusion, where medication was administered to a specified site through an indwelling catheter. Furthermore, the applicability of continuous regional arterial infusion therapy in pediatric AP is discussed, aiming to contribute to advancements in the diagnosis and management of AP in children.