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肾小管重塑在急性肾损伤中的作用机制

  • 沈云琳 ,
  • 黄文彦
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  • 上海交通大学附属儿童医院 上海市儿童医院肾脏风湿科( 上海 200040)

收稿日期: 2014-09-15

  网络出版日期: 2014-09-15

The role of renal tubule remodeling in acute kidney injury

  • SHEN Yunlin ,
  • HUANG Wenyan
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  • Department of Nephrology and Rheumatology, Shanghai Children’s Hospital, Shanghai Jiaotong University, Shanghai 200040,China

Received date: 2014-09-15

  Online published: 2014-09-15

摘要

急性肾损伤(AKI)是临床常见的危重症,病死率高。AKI时主要的受损细胞是肾小管上皮细胞。肾小管上皮细胞重塑在AKI发生发展、预后转归中起着至关重要的作用。肾小管重塑过程机制复杂,其确切调控机制尚不清楚,文章就AKI肾小管重塑调控机制进行综述。

本文引用格式

沈云琳 , 黄文彦 . 肾小管重塑在急性肾损伤中的作用机制[J]. 临床儿科杂志, 2014 , 32(9) : 895 . DOI: 10.3969 j.issn.1000-3606.2014.09.024

Abstract

 Acute kidney injury (AKI) has emerged as a major public health problem that leads to decreased survival. Renal tubular epithelial cells are mainly damaged cells in AKI. Renal tubular epithelial cell remodeling plays a vital role in AKI. The regulatory mechanism of renal tubule remodeling is not yet clear. This review is written to address the renal tubule remodeling regulation mechanism of AKI.
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