文献综述

胰石蛋白在胰腺损伤及脓毒症中的意义

  • 彭红艳 ,
  • 祝益民
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  • 南华大学儿科学院 湖南省儿童医院 ( 湖南长沙 410007)

收稿日期: 2014-11-15

  网络出版日期: 2014-11-15

Significance of pancreatic stone protein in pancreatic injury and sepsis

  • PENG Hongyan ,
  • ZHU Yimin
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  • Pediatric College of Hunan Provincial Children's Hospital, Nanhua University, Changsha 410007, Hunan, China

Received date: 2014-11-15

  Online published: 2014-11-15

摘要

 胰石蛋白(PSP)主要由胰腺腺泡细胞合成和分泌,是胰腺外分泌产物,胃肠细胞等也分泌少量,属于胰腺分泌的应激蛋白家族成员之一。PSP在急慢性胰腺炎、糖尿病、炎症性肠病及消化道肿瘤等患者中升高。近年来,一些研究表明其在胰腺损伤及脓毒症中有潜在的临床价值。文章对胰石蛋白在胰腺损伤及脓毒症中研究进展作一综述。

本文引用格式

彭红艳 , 祝益民 . 胰石蛋白在胰腺损伤及脓毒症中的意义[J]. 临床儿科杂志, 2014 , 32(11) : 1093 . DOI: 10.3969 j.issn.1000-3606.2014.11.023

Abstract

 Pancreatic stone protein (PSP) is the product of exocrine pancreas mainly synthesized and secreted by the pancreas acinar cells, a small amount secreted by gastrointestinal cells. PSP is one of stress protein family members secreted in the pancreas. PSP increased in acute and chronic pancreatitis, diabetes, inflammatory bowel disease and gastrointestinal tumors. In recent years, some studies showed that PSP has potential clinical value in pancreatic injury and sepsis. In this article, we reviewed the progress of pancreatic stone protein in pancreatic injury and sepsis.
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