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儿童良性癫痫伴中央颞区棘波变异型12 例临床分析

  • 宁泽淑 ,
  • 江志 ,
  • 陈波 ,
  • 张洁 ,
  • 杨理明
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  • 湖南省儿童医院神经一科( 湖南长沙 410007)

收稿日期: 2015-05-15

  网络出版日期: 2015-05-15

Clinical features of the variants of benign childhood epilepsy with central temporal spikes: 12 cases report

  • NING Zeshu ,
  • JIANG Zhi ,
  • CHEN Bo ,
  • ZHANG Jie ,
  • YANG Liming
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  • Department of Neurology, Hunan Children’s Hospital, Changsha 410007, Hunan, China

Received date: 2015-05-15

  Online published: 2015-05-15

摘要

目的 探讨儿童良性癫痫伴中央颞区棘波(BECT)变异型的临床特征。方法 回顾性分析2007年1月至2014年1月收治的12例BECT变异型患儿的临床资料。结果 12例患儿中男7例、女5例,其中2例为双卵龙凤胎,起病年龄为3~9岁。病程中出现不典型失神10例,负性肌阵挛8例,言语障碍和口咽部失用4例。视频脑电图监测均显示清醒及睡眠期Rolandic区棘慢波大量发放,慢波睡眠期指数达50%~85%。结论 BECT变异型均伴有明显的脑电图恶化,认识其临床和脑电图变化的特点及规律,可提高对BECT变异型的诊断。

本文引用格式

宁泽淑 , 江志 , 陈波 , 张洁 , 杨理明 . 儿童良性癫痫伴中央颞区棘波变异型12 例临床分析[J]. 临床儿科杂志, 2015 , 33(5) : 470 . DOI: 10.3969 j.issn.1000-3606.2015.05.018

Abstract

 Objective To study the clinical features of the variants of benign childhood epilepsy with central temporal spikes (BECT). Methods The clinical data of 12 hospitalized pediatric patients with BECT from Jan 2007 to Jan 2014 were retrospectively reviewed. Results There were 7 boys and 5 girls in 12 patients. The age of onset was from 3 to 9 years old. Two cases were dizygotic twins. The atypical symptoms included atypical absence of 10 cases, negative myoclonic seizure of 8 cases, speech expression disorders and oral-pharynx apraxia of 4 cases. The electroencephalography (EEG) of all 12 patients showed abundance of spike and waves (SW) in rolandic areas during wake-up and sleep. The SW index was 50%-85% during slow sleep in all patients. Conclusions The variants of BECT are often associated with EEG deterioration. Understanding the clinical featuress and EEG characteristics can help the diagnosis of BECT variants.
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