长期输血导致的铁过载相关心脏损害是重型地贫患者的主要死亡原因。如果能及时发现铁过载导致的心脏疾患，进行有效的铁螯合治疗，将大大提高患者的生存率。文章介绍现有铁过载心脏损害评估方法，尤其是心脏磁共振检查在铁过载心脏损害检测方面的重要意义。

Cardiac involvement related to iron overload caused by long-term blood transfusion is a major cause of death for patients with thalassemia major. Patients’ survival will be improved greatly if cardiomyopathy resulted from transfusional iron overload could be detected timely and effective iron chelation be initiated promptly. In the present article, various evaluation methods currently used in clinical practice are reviewed, with particular focus on cardiac MRI for the monitoring of myocardial involvement related to iron overload.