专家笔谈

宫内感染与新生儿脑损伤

  • 母得志 ,
  • 石晶
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  • 四川大学华西第二医院儿童医学中心(四川成都 610041)

收稿日期: 2015-09-15

  网络出版日期: 2015-09-15

Intrauterine infection and neonatal brain damagev

  • MU Dezhi ,
  • SHI Jing
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  • Clinical Centeral of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan, China

Received date: 2015-09-15

  Online published: 2015-09-15

摘要

宫内感染是导致新生儿脑损伤及神经系统功能障碍的重要危险因素。病毒、细菌和原虫可感染子宫腔并导致胎儿和新生儿脑损伤。炎症反应是宫内感染致新生儿脑损伤的重要致病因素,不同孕期宫内感染导致不同类型脑损害。临床医师应重视孕期宫内感染的预防,有必要进一步加强临床和基础研究,探索宫内感染致新生儿脑损伤的有效干预措施。

本文引用格式

母得志 , 石晶 . 宫内感染与新生儿脑损伤[J]. 临床儿科杂志, 2015 , 33(9) : 767 . DOI: 10.3969 j.issn.1000-3606.2015.09.002

Abstract

Intrauterine infection is an important risk factor for neonatal brain damage and neurological dysfunction. Viruses, bacteria, and protozoa can cause intrauterine infection which results in neonatal brain damage. The inflammatory response is an important pathogenic factor for neonatal brain damage caused by intrauterine infection. Intrauterine infection in different periods of pregnancy might cause different types of brain damage in neonates. Clinicians should pay attention to the prevention of intrauterine infection during pregnancy. It is necessary to further strengthen the clinical and basic research to explore effective interventions for neonatal brain damage caused by intrauterine infection.
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