消化系统疾病专栏

轻度胃肠炎伴婴幼儿良性惊厥264 例临床分析

  • 张瑜 ,
  • 冀超玉 ,
  • 李荣敏 ,
  • 韩立坡 ,
  • 张远达 ,
  • 董青伟 ,
  • 张小龙
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  • 保定市儿童医院(河北保定 071000)

收稿日期: 2015-10-15

  网络出版日期: 2015-10-15

Clinical analysis of 264 cases of benign infantile convulsions associated with mild gastroenteritis 

  • ZHANG Yu ,
  • JI Chaoyu ,
  • LI Rongmin ,
  • HAN Lipo ,
  •  ZHANG Yuanda ,
  • DONG Qingwei ,
  • ZHANG Xiaolong
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  • Baoding Children’s Hospital, Baoding 071000, Hebei, China

Received date: 2015-10-15

  Online published: 2015-10-15

摘要

目的 分析轻度胃肠炎伴婴幼儿良性惊厥(BICE)复发以及转化为癫痫的可能危险因素。方法 将264例BICE患儿按惊厥发生次数分为单次组134例(惊厥1次),多发组130例(惊厥次数≥2次);按惊厥持续时间分为,短时组186例(惊厥持续时间<5 min),长时组78例(惊厥时间≥5 min),分析其住院及随访资料。结果 多发组有9.23%复发,6.15%转化为癫痫;单次组有2.99%复发,0.75%转化为癫痫,两组间复发及转化为癫痫比例的差异均有统计学意义(P均<0.05)。长时组有12.82%复发,8.97%转化为癫痫;短时组有3.23%复发,1.08%转化为癫痫,两组间复发及转化为癫痫比例的差异均有统计学意义(P均<0.01)。结论 BICE患儿有复发以及转化为癫痫的可能,惊厥次数≥2次,惊厥持续时间≥5 min是BICE患儿复发以及转化为癫痫的可能危险因素。

本文引用格式

张瑜 , 冀超玉 , 李荣敏 , 韩立坡 , 张远达 , 董青伟 , 张小龙 . 轻度胃肠炎伴婴幼儿良性惊厥264 例临床分析[J]. 临床儿科杂志, 2015 , 33(10) : 857 . DOI: 10.3969 j.issn.1000-3606.2015.10.005

Abstract

 Objective  To analyze the potential risk factors for relapse and development of epilepsy in patients with benign infantile convulsions associated with mild gastroenteritis (BICE). Methods A total of 264 cases of BICE were recruited. According to the frequency of convulsions, the patients were divided into single group (n=134, convulsion once), and multiple group (n=130, convulsions ≥ 2 times). According to convulsion duration, the patients were divided into short-term group (n=186, convulsions duration <5 minutes) , and long-term group (n=78, convulsion duration ≥ 5 minutes). The clinical data obtained during hospitalization and follow-up were analyzed. Results In multiple group, 9.23% were relapsed and 6.15% developed epilepsy. In single group, 2.99% were relapsed and 0.75% developed epilepsy. There were significantly different in the rate of relapses and development of epilepsy between two groups (P<0.05). In the long-term group, 12.82% were relapsed and 8.97% developed epilepsy. In the short-term group, 3.23% were relapsed and 1.08% developed epilepsy. There were significantly different in the rate of relapses and development of epilepsy between the two groups (P<0.05). Conclusions There are the risks of relapse and development of epilepsy in BICE patients. Convulsions ≥ 2 times and ≥ 5 minutes may be the risk factors of relapse and development of epilepsy.
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