目的 分析手足口病(HFMD)合并川崎病(KD)患儿的临床特点。方法 回顾性分析2013 年6 月—2015年6 月就诊的7 例HFMD 合并KD 患儿的临床资料。结果 7 例患儿中5 例球结膜充血,6 例口唇红、皲裂、杨梅舌。2 例符合典型KD 诊断标准,5 例符合不完全KD 诊断标准。7 例患儿脑脊液结果均符合病毒性脑炎。咽拭子培养5 例肠道病毒71 型(EV71)阳性,1 例柯萨奇病毒A16(CVA16)阳性。6 例合并冠状动脉损伤,2 例右束支传导阻滞。结论 HFMD 合并KD 患儿多为不完全KD,常合并中枢神经系统感染以及冠状动脉损伤。
Objective To analyze the clinical characteristics of children with hand, foot, and mouth disease (HFMD) combined with Kawasaki disease (KD). Methods Clinical data of 7 pediatric patients with HFMD combined KD were retrospectively analyzed from June 2013 to June 2015. Results Among this 7 patients, 5 patients were with bulbar conjunctival congestion and 6 patients were with cracked lips and strawberry-like tongue. Two patients met the diagnostic criteria of typical KD, 5 cases met the diagnostic criteria of incomplete KD. The testing results of cerebrospinal fluid from 7 patients all were consistent with viral encephalitis. There were 5 patients with EV71 positive, one patient with CVA16 positive. Six patients had coronary arterial lesions, two patients with right bundle branch block. Conclusion Most of the children with HFMD combined KD was incomplete KD, complicated with central nervous system infections and coronary arterial lesions.