维甲酸（RA）受体是一组配体依赖的核转录调节因子，广泛分布在各类组织细胞中，其不同亚型之间可形成同源性或异源性二聚体，参与胚胎发育、细胞增殖、分化、凋亡等病理生理过程。在不同细胞或组织中，RA受体的表达与疾病的关系不尽相同。近年研究认为，RA受体与肾脏疾病的发生发展关系密切。文章综述RA受体及其信号通路在肾脏疾病发生发展中的作用。

Retinoic acid (RA) receptor, is a group of ligand-regulated nuclear transcription factors and widely distributed in various tissue cells. The different subtypes of RA receptor can polymerize into homologous or heterogenous dimmers, and then participate in the physiological and pathological processes of embryonic development, cell proliferation and differentiation, and apoptosis. However, the relationship between the expression of RA receptor and the diseases is different in diverse cells or tissues. Recent researches demonstrated that RA receptor is closely related to the pathogenesis and development of renal diseases. This article aims to review the role of the RA receptor and its signal pathway in the development of renal diseases.