目的 探讨湿疹患儿及其家庭治疗前后的生活质量。方法 将湿疹患儿分为食物过敏组（FA组，46例）及非 食物过敏组（N-FA组，47例）。 应用湿疹面积及严重度指数（EASI） 对患儿进行评估；对两组湿疹患儿进行规范化干预治 疗2个月后，采用食物过敏生活质量问卷-父母版（FAQLQ-PF）和婴儿皮肤病生活质量指数量表（IDQOL）评估治疗前后 的生活质量。结果 两组患儿在年龄、性别、过敏家族史及喂养方式的差异无统计学意义（P均 ＞ 0.05）；FA组中鸡蛋过 敏34 例（73.91%），牛奶过敏20例（43.48%），胡萝卜过敏2例（4.35%）。 两组患儿的EASI、FAQLQ、IDQOL评分在治疗 后均有显著下降，与治疗前比较，差异有统计学意义（P均 ＜ 0.05）。 治疗前，FA组FAQLQ-PF各模块及总分与N-FA组的 差异无统计学意义（P均 ＞ 0.05）；治疗两个月后，FA组FAQLQ总分（1.33 ± 1.08）较N-FA组（0.79 ± 0.80）高，差异有统 计学意义（Z ＝ 2.83， P ＝ 0.005）；FA组在情绪影响、食物的焦虑、社交/饮食限制模块与N-FA组比较差异亦有统计学意义 （Z ＝ 2.13～2.89， P均 ＜ 0.05）。 结论 食物过敏患儿的家长更易担心患儿的情绪变化及社交、饮食受到限制。FAQLQ-PF 对于食物过敏生活质量的评估更具特异性。

Objective To explore life quality of infants with eczema and their families before and after treatment. Methods The infants with eczema were divided into food allergic group (FA group, n=46) and non-food allergic group (N-FA group, n=47). The eczema was evaluated by the areas of eczema and severity index (EASI). After 2 months of standardized intervention, the quality of life before and after treatment were assessed by the Food Allergy Quality of Life Questionnaire-Parent Form (FAQLQ-PF) and the Infant’s Dermatitis Quality of Life Index (IDQOL). Results There was no difference between the two groups in age, gender, family history of allergy and feeding patterns (all P ＞  0.05). In FA group, there were 34 cases (73.91%) of egg allergy, 20 cases (43.48%) of milk allergy and 2 cases (4.35%) of carrot allergy. After the intervention, the scores of EASI, FAQLQ, and IDQOL were decreased obviously in the two groups, and there were statistical difference before and after treatment ( P all < 0.05). Before treatment, the total score and each part of FAQLQ-PF in FA group was similar with N-FA group ( P all ＞  0.05); After two months of intervention, the total score of FAQLQ in FA group was higher than that in N-FA group (Z =2.83, P =0.005); the subscales of emotional impact, anxiety about food, and social/dietary restrictions were also significantly different between FA group and N-FA group (Z = 2.13-2.89, all P < 0.05). Conclusions Parents of infants with food allergies are more likely to worry about infant's emotional changes and social, dietary restrictions. FAQLQ-PF is more specific for assessing the quality of life in food allergies.