目的　探讨严重食物过敏性胃肠病患儿的粪菌移植治疗。方法　回顾1例严重食物过敏性胃肠病患儿的粪 菌移植治疗过程，并复习相关文献。结果　患儿，男， 2岁，以肠道感染起病，予以足疗程抗感染及对症支持治疗，腹泻仍 迁延不愈，最终给予粪菌移植治疗后，好转出院，随访2个月未见不良反应。检索国外文献，儿童粪菌移植主要应用于难辨 梭状芽孢杆菌感染（CDI）和炎症性肠病（IBD）中，有效率分别为90%~100%和55.6%~100%；而国内文献中，粪菌移植 在儿童中主要用于CDI和抗生素相关性腹泻病中，有效率100%，均未见严重不良反应。 结论　粪菌移植治疗儿童严重食 物过敏性胃肠病短期安全有效，但其在儿童中的应用技术还不成熟，需要更多、更深入的研究。

　Objective　To explore fecal bacteria transplantation for the treatment of severe gastrointestinal disease caused by food allergy. Method　The therapeutic process of fecal bacteria transplantation for treatment of severe food allergy gastrointestinal disease was retrospectively analyzed, and the related literature was reviewed. Results　A 2-year-old boy had onset of intestinal infection and diarrhea was persistent even though he had received adequate anti-infection therapy and supportive treatment. Finally, the patient received the treatment of fecal bacteria transplantation and the symptoms were then improved. No adverse reactions were observed in 2 months of follow-up. In foreign literature, fecal bacteria transplantation in children is mainly applied to clostridium difficile infection (CDI) and inflammatory bowel disease (IBD), with efficiency of 90% - 100% and 55.6% - 100%, respectively. While in the domestic literature, fecal bacteria transplantation in children is mainly used in CDI and antibiotic associated diarrhea, and the effective rate is 100%. No serious adverse reactions were found in all the researches. Conclusion　Fecal transplantation is safe and effective in the treatment of children with severe gastrointestinal disease caused by food allergy, but its application in children is not yet mature and needs more in-depth researches.