脊髓性肌萎缩症患者脊柱矫形围手术期治疗药物管理

doi:10.12372/jcp.2025.24e1160

Abstract

Abstract:

Spinal muscular atrophy (SMA), a devastating hereditary neuromuscular disease, is often complicated by scoliosis. While scoliosis correction surgery is frequently indicated to correct spinal deformities, it is not without significant risks, including the potential for infection, hemorrhage, and neurological damage. Consequently, the management of perioperative medications is of paramount importance for the prevention and control of these complications, as well as for facilitating patient recovery. However, the distinctive physiological and pathological characteristics of SMA, coupled with the lack of standardized protocols, present considerable challenges in perioperative medication management. This review article offers an in-depth examination of the perioperative medication therapy management for patients with SMA undergoing scoliosis surgery. It aims to establish an evidence-based framework and provide a reference for the judicious use of drugs in clinical settings.

Key words: spinal muscular atrophy, scoliosis correction surgery, perioperative period, medication therapy management

XING Xiaodong, LIU Yan, LIU Xinzhu, JIANG Wengao, ZHANG Jian. Medication therapy management of patients with spinal muscular atrophy during the perioperative period of scoliosis correction surgery[J].Journal of Clinical Pediatrics, 2025, 43(1): 70-76.

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Medication therapy management of patients with spinal muscular atrophy during the perioperative period of scoliosis correction surgery

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