Abstract: Objective　To explore the safe method of radiofrequency catheter ablation (RFCA) for treatment of atrioventricular nodal reentrant tachycardia (AVNRT) in children. Methods　The clinical data of 80 AVNRT children who received RFCA under the guidance of CARTO3 system from January 2014 to April 2017 were retrospective analyzed. Results Eighty AVNRT children (48 boys and 32 girls) had an average age of 11.74 ± 2.49 years and mean weight of 42.19 ± 12.97 kg. The weight of 6 cases (7.5%) was less than 27 kg. The average fluoroscopy time during the treatment was 6.87±7.09 min with radiation doses at 10.71±7.02 mGy and procedure time at 80.81±29.14 min. The immediate successful rate was 98.75% (1/80). The recurrence rate was 1.25% (1/80) during follow-up and the complication rate was 1.25% (1/80), and there was no death case. Conclusions　Under the guidance of the CARTO3 system, combined with anatomical and electrophysiological methods, energy titration approach of RFCA is safe and effective treatment of AVNRT.