Abstract: 　Objective　To explore the clinical characteristics, diagnosis, treatment and prognosis of serous eosinophilic gastroenteritis (EGE) in children, and to improve diagnosis and therapy of it. Methods　The data of clinical manifestation, laboratory examination, endoscopy, biopsy, management and prognosis from one boy with serous type of EGE were retrospectively analyzed. The Chinese databases and PubMed databases were searched for serous type of EGE in the last ten years for literature review. Results　A 16-years-old boy with serosal type of EGE show nonspecific gastrointestinal symptoms such as abdominal pain and abdominal distension. EOS counts in peripheral blood and bone marrow were significantly increased. A large number of EOS were found in his ascites. A large number of EOS can be seen in the serous layer of the intestine from laparoscopic sampling. This boy needs long-term and low dose hormone maintenance. There are 16 articles about serous disease type of EGE found in the domestic and foreign databases. Ascites is the most commonly seen symptom for serous type of EGE. Hormone therapy is sensitive, and the clinical symptoms reappear easily along with the hormone reduction or withdrawal. Some children need longterm maintenance of low dose glucocorticoid. Conclusions　Ascites is the most commonly seen symptom for serous type of EGE. Increased EOS in serosal tissue is the key for pathological diagnosis. Hormone therapy is sensitive, and the clinical symptoms reappear easily along with hormone reduction or withdrawal. Some children need long-term maintenance of low dose glucocorticoid.

Key words: eosinophilic gastroenteroenteritis;　serous;　child