Expression of CNP/NPR-B axis and NPR-C/NEP elimination pathways in rats with unilateral ureteral obstruction
ZHAO Xueqi1, WANG Jing2, KONG Haibo1, HU Bo1, HU Peng1
(1. Department of Pediatrics, The First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, China; 2. Nanjing Children's Hospital, Nanjing 210000, Jiangsu, China)
[1] Sudoh T，Minamino N，Kangawa K，et al. C-type natriuretic peptide (CNP)：a new member of natriuretic peptide family identi?ed in porcine brain [J]. Biochem Biophys Res Commun，1990,168(2)：863-870. [2] Johnson KR，Hoagland TM，Olson KR. Endogenous vascular synthesis of B-type and C-type natriuretic peptides in the rainbow trout [J]. J Exp Biol，2011，214(Pt 16)：2709-2717. [3] Hodgkins KS，Schnaper HW. Tubulointerstitial injury and the progression of chronic kidney disease [J]. Pediatr Nephrol，2012，27(6)：901-909. [4] Das S，Au E，Krazit ST，et al. Targeted disruption of guany-lyl cyclase-A/natriuretic peptide receptor-A gene provokes renal fibrosis and remodeling in null mutant mice：role of proinflammatory cytokines [J]. Endocrinology，2010，151(12)：5841-5850. [5] Hu P，Wang J，Hu B，et al. Increased urinary C-type natriuretic peptide excretion may be an early marker of renal tubulointerstitial fibrosis [J]. Peptides，2012，37(1)：98-105. [6] Hu P，Zhao XQ，Wang J，et al. Simplified stereological evaluation of renal morphology after unilateral ureteral obstruction [J]. Int J Med Sci，2013，10(4)：385-391. [7] Chevalier RL. Molecular and cellular pathophysiology of obstructive nephropathy [J]. Pediatr Nephrol，1999，13(7)：612-619. [8] Picard N，Baum O，Vogetseder A，et al. Origin of renal myofibroblasts in the model of unilateral ureter obstruction in the rat [J]. Histochem Cell Biol，2008，130(1)：141-155. [9] Ogata Y，Ishidoya S，Fukuzaki A，et al. Upregulated expression of transforming growth factor-beta，type IV collagen，and plasminogen activator inhibitor-1 mRNA are decreased after release of unilateral ureteral obstruction [J]. Tohoku J Exp Med，2002，197(3)：159-168. [10] Kimura M，Asano M，Abe K，et al. Role of atrophic changes in proximal tubular cells in the peritubular deposition of type IV collagen in a rat renal ablation model [J]. Nephrol Dial Transplant，2005，20(8)：1559-1565. [11] Xie P，Sun L，Nayak B，et al. C/EBP-beta modulates transcription of tubulointerstitial nephritis antigen in obstructive uropathy [J]. J Am Soc Nephrol，2009，20(4)：807-819. [12] Hu P，Qin YH，Pei J，et al. Beneficial effect of all-trans retinoic acid (ATRA) on glomerulosclerosis rats via the down-regulation of the expression of alpha-smooth muscle actin：a comparative study between ATRA and benazepril [J]. Exp Mol Pathol，2010，89(1)：51-57. [13] Kim SW，Li Y，Kim S，et al. Local renal and vascular natriuretic peptide system in obstructive uropathic rats [J]. Urol Res，2002， 30(2)：97-101. [14] Surendran K，Simon TC. CNP gene expression is activated by Wnt signaling and correlates with Wnt4 expression du-ring renal injury [J]. Am J Physiol Renal Physiol，2003，284(4)：F653-F662. [15] Chauhan SD，Nilsson H，Ahluwalia A，et al. Release of C-type natriuretic peptide accounts for the biological activity of endothelium-derived hyperpolarizing factor [J]. Proc Natl Acad Sci U S A，2003，100(3)：1426-1431. [16] Hu P，Wang J，Zhao XQ，et al. Overexpressed C-type natriure-tic peptide serves as an early compensatory response to counteract extracellular matrix remodeling in unilateral ureteral obstruction rats [J]. Mol Biol Rep，2013，40(2)：1429-1441. [17] Koller KJ，Lowe DG，Bennett GL，et al. Selective activation of the B natriuretic peptide receptor by C-type natriuretic peptide (CNP) [J]. Science,1991，252(5002)：120-123. [18] Doi K，Ikeda T，Itoh H，et al. C-type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelialization [J]. Arterioscler Thromb Vasc Biol，2001，21(6)：930-936. [19] Potter LR，Abbey-Hosch S，Dickey DM. Natriuretic peptides，their receptors，and cyclic guanosine monophosphate-dependent signaling functions [J]. Endocr Rev，2006，27(1)：47-72. [20] Kramer HJ，B?cker A，Bokemeyer D，et al. Atrial natriuretic peptide and endothelin：modulators of renal function [J]. Clin Investig，1994，72(9)：703-705. [21] Woodard GE，Li X，Rosado JA. Characteristics of the renal C-type natriuretic peptide receptor in hypertrophied and deve-loping rat kidney [J]. J Mol Endocrinol，2005，35(3)：519-530. [22] Nagase M，Ando K，Katafuchi T，et al. Role of natriuretic peptide receptor type C in Dahl salt-sensitive hypertensive rats [J]. Hypertension，1997，30(2 Pt 1)：177-183. [23] Jalal F，Lemay G，Zollinger M，et al. Neutral endopeptidase，a major brush border protein of the kidney proximal nephron，is directly targeted to the apical domain when expressed in Madin-Darby canine kidney cells [J]. J Biol Chem，1991，266(29)：19826-19832. [24] Hu P，Xuan Q，Hu B，et al. Anti-neutral endopeptidase，natriure-tic peptides disarrangement，and proteinuria onset in membranous nephropathy [J]. Mol Biol Rep，2013，40(4)：2963-2967. [25] Floras JS. Vasopeptidase inhibition：a novel approach to cardiovascular therapy [J]. Can J Cardiol，2002，18(2)：177-182. [26] Nakhoul F，Ramadan R，Khankin E，et al. Glomerular abundance of nephrin and podocin in experimental nephrotic syndrome：different effects of antiproteinuric therapies [J]. Am J Physiol Renal Physiol，2005，289(4)：F880-F890. [27] Wenzel UO，Wolf G，Jacob I，et al. Beneficial and adverse renal and vascular effects of the vasopeptidase inhibitor omapatrilat in renovascular hypertensive rats [J]. Nephrol Dial Transplant，2003，18(10)：2005-2013.
