[1] Hood B,Bigler S,Bishop P,et al. Juvenile polyps and Juvenile polyp syndromes in children:a clinical and endoscopic survey [J]. Clin Pediatr,2011,50(10):910-915. [2] Cheng H,Zhang T,Gu W,et al. The presence of Helicobacter pylori in colorectal polyps detected by immunohistochemical methods in children [J]. Pediatr Infect Dis J,2012,31(4):364-367. [3] Iwamoto M,Hoffenberg EJ,Carethers JM,et al. Nuclear accumulation of β-catenin occurs commonly in the epithelial cells of juvenile polyps [J]. Pediatr Res,2005,57(1):4-9. [4] Coelho TR,Almeida L,Lazo PA,et al. JC virus in the pathogenesis of colorectal cancer,an etiological agent or another component in a multistep process? [J]. Virol J,2010,7:42. [5] Lin PY,Fung CY,Chang FP. Prevalence and genotype identification of human JC virus in colon cancer in Taiwan [J]. J Med Virol,2008,80(10):1828-1834. [6] Jung WT,Li MS,Goel A,et al. JC virus T-antigen expression in sporadic adenomatous polyps of the colon [J]. Cancer,2008,112(5):1028-1036. [7] Mou X,Chen L,Liu F,et al. Prevalence of JC virus in chinese patients with colorectal cancer [J]. PLoS One,2012,7(5):e35900. [8] Theodoropoulos G,Panoussopoulos D,Papaconstantinou I,et al. Assessment of JC polyoma virus in colon neoplasms [J]. Dis Colon Rectum,2005,48(1):86-91. [9] Vilkin A,Ronen Z,Levi Z,et al. Presence of JC virus DNA in the tumor tissue and normal mucosa of patients with sporadic colorectal cancer (CRC) or with positive family history and Bethesda criteria [J]. Dig Dis Sci,2012,57(1):79-84. [10] Newcomb PA,Bush AC,Stoner GL,et al. No evidence of an association of JC virus and colon neoplasia [J]. Cancer Epidemiol Biomarkers Prev,2004,13(4):662-666. [11] White MK,Khalili K. Expression of JC virus regulatory proteins in human cancer:potential mechanisms for tumourige-nesis [J]. Eur J Cancer,2005,41(16):2537-2548. [12] Gan DD,Khalili K. Interaction between JCV large T-antigen and beta-catenin [J]. Oncogene,2004,23(2):483-490. [13] Reiss K,Khalili K,Giordano A,et al. JC virus large T-antigen and IGF-1 signaling system merge to affect DNA repair and genomic integrity [J]. J Cell Physiol,2006,206(2):295-300.