Abstract: Objective　To explore the changes in the levels of coagulation indicators and procalcitonin (PCT) in children with severe pneumonia. Methods A total of 76 children with severe pneumonia were selected and were divided into two groups according to the level of PCT, PCT<2.00 ng/ml group and PCT ≥ 2.00 ng/ml group. Thirty healthy children were selected as normal controls. The levels of PCT, platelet counts (PLT), antithrombin- Ⅲ (AT- Ⅲ ) activity and D-dimer (DD) were measured and compared among groups. Results Compared with control group, PCT, PLT and DD levels were significantly higher and AT- Ⅲ activity was significantly lower in severe pneumonia group (P<0.05). AT- Ⅲ activity and PLT were significantly lower and DD level was significantly higher in PCT≥2.00 ng/ml group than those in PCT<2.00 ng/ml group (P<0.05). The incidence of disseminated intravascular coagulation (DIC) in PCT≥2.00ng/ml group was significantly higher than that in PCT<2.00ng/ml group (33.33% vs. 9.09%, corrected χ2=5.02, P=0.025). Conclusions There is dysfunction of coagulation in children with severe pneumonia. The higher level of PCT is, more obvious coagulation dysfunction is. The severe pneumonia children with high level of PCT are more likely to be complicated with disseminated inravascular coagulation.