Abstract: Objective　To analyze the relationship between clinical and pathological features in children with Henoche-Schönelin purpura nephritis (HSPN). Methods Clinical and pathological data of 89 children with HSPN from April 2009 to April 2013 in our hospital were retrospectively analyzed. Results A majority of patients (94.83%) suffered nephritis within two month after purpura. Clinically, hematuria and proteinuria (41.6%), nephrotic syndrome (27.0%), and isolated proteinuria (21.3%) are the most common type in children with HSPN. The majority of pathological changes of these three types HSPN are grade Ⅲ , which accounts for 67.6%, 70.8%, and 73.7%, respectively. The clinical manifestations are closely associated with pathologic classification (H=26.88, P=0.000). IgA plus IgM deposit was the most common type (40.45%) in histological and immunopathologic changes.There was no statistical difference between the pathologic classification and immunopathologic types. Gastrointestinal bleeding was associated with pathologic classification. Conclusions The pathological changes of HPSN patients are mainly of grades Ⅱ and Ⅲ , and the clinical manifestations, gastrointestinal bleeding in particular, are closely associated with pathological classification.