Abstract: Objective　To explore the predictive value of acute care of at-risk newborns respiratory score (ACoRN) and the score for neonatal acute physiology with perinatal extension-II (SNAPPE-II ) for the severity of respiratory diseases in the late preterm and term infants. Method　A retrospective analysis was performed on the data of the late preterm and term infants within the first 24 hours after birth in the Second Department of Neonatology in Lanzhou University Second Hospital from June 2017 to June 2018. The data of ACoRN score and SNAPPE-II score was calculated, and the infants were divided into respiratory disease group and non-respiratory disease group. The respiratory disease group was further divided into the transient tachypnea of newborn (TTN) group and the other respiratory disease groups. Univariate analysis, logistic regression and receiver operating characteristic curve (ROC) were used to analyze different groups of those infants. Results　There were 89 cases in the TTN group, 33 cases in the other respiratory disease group and 137 cases in the non-respiratory disease group. The mean gestational age was (37.02±2.16) weeks, mean birth weight was (2.72±0.61) kg. Univariate analysis showed that 1 minute Apgar score, 5 minutes Apgar score, pulmonary surfactant, antibiotic treatment, non-invasive assistant ventilation, invasive assistant ventilation, ACoRN score and SNAPPE-II score had significant differences statistically (P < 0.05). Logistic regression analysis showed that 1 minute Apgar score, length of stay, ACoRN score and SNAPPE-II score were correlated with the respiratory disease group compared with the non-respiratory disease group (P <0.05). ROC analysis showed that the efficiency of the score of ACoRN correlated with SNAPPE-II was the highest (AUC=0.991) than that of ACoRN (AUC=0.972) and that of SNAPPE-II (AUC=0.550) separately. Conclusion　ACoRN score and SNAPPE-II score was based on a rapid, simple evaluation method respectively from the aspects of breathing and acute physiological characteristics. ACoRN correlated with SNAPPE-II score was as a predictive index, benefitting to comprehensively judge for the abnormal degree of neonatal respiratory diseases and the indication of transporting to the neonatal intensive care unit.

Key words: 　ACoRN score;　SNAPPE-II score;　late preterm and term infants;　respiratory disease