Journal of Clinical Pediatrics ›› 2020, Vol. 38 ›› Issue (3): 205-.doi: 10.3969/j.issn.1000-3606.2020.03.011

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Takayasu’s arteritis in children: a case report

 ZHANG Yuesheng1, LI Junfeng2, YAN Suqi1, TANG Jianqiao1, WU Zhi1, LI Hong1, ZHOU Lishan1, Zhang Linli1, XIONG Xiaoli1, LI Jianjun3   

  1. 1.Department of Integrative Chinese and Westerm Medicine, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430016, Hubei, China; 2.Traditional Chinese Medicine Department, Qingdao Women and Children’s Hospital, Qingdao 266034, Shandong, China; 3. Depratment of Radiology, Tongji Hospital of Tongji Medical College, Huanzhong University of Science and Technology, Wuhan 430030, Hubei, China
  • Published:2020-04-07

Abstract: Objective To explore the clinical characteristics of Takayasu’s arteritis in children. Method The clinical data of Takayasu’s arteritis in a child were analyzed, and the relevant literatures were reviewed. Results The 7-year-old girl had recurrent fever of unknown causes, and the inflammatory indicators were significantly increased, and the anti-infection treatment was ineffective. PET-CT was performed and vasculitis was considered. After receiving glucocorticoid therapy, the patient's condition was recurrent, and angiography was performed to confirm the diagnosis of arteritis. Subsequently, the patient had surgical operation, and treated with glucocorticoids and cyclophosphamide, and no recurrence occurred. Conclusions For those with unexplained fever, accompanied by elevated inflammatory indicators and ineffective anti-infective treatment, clinician should be alert to the possibility of Takayasu’s arteritis. Early PET-CT examination and treatment by combination of glucocorticoid and cyclophosphamide after diagnosis can effectively improve the prognosis.

Key words:  Takayasu’s arteritis; fever; PET-CT; child