Abstract: Objective　To investigate the clinical features, treatment response and prognosis in patients with Takayasu arteritis in children. Methods　Ten pediatric patients with Takayasu arteritis admitted into our hospital from 2014 to 2019 were retrospectively evaluated in clinical features, laboratory testing, imaging examinations, treatment response and prognosis of the disease. Results　There were five boys and five girls in ten patients with Takayasu arteritis. The onset age was from three months to 14.9 years old. Hypertension was the most common finding on first presentation (80%), followed by blood pressure discrepancy (70%), vascular bruits (60%), fever (60%), acrotism or pulseless (50%), claudication (40%), headache (30%) and stomachache (30%). The active indices of inflammation were increased. It showed increased ESR in 9 cases, increased CRP in 8 cases and increased WBC in 7 cases. The distribution of angiographic finding was as follows: six cases with type V three cases with type III and one case with type I. Nine patients were treated with steroids and/or immunosuppressive agents and one patient was treated with biological agent. Two cases died, two cases were lost to follow-up, and two cases showed no improvement and the other four cases were improved. Conclusion　Takayasu arteritis is a rare and potentially life-threatening disease in children, patients with sustained high levels of acute-phase reactants, including ESR and CRP, should be given comprehensive examination, especially those with hypertension, pulseless and vascular bruits. Angiography also should be done to confirm the diagnose of Takayasu arteritis.

Key words: 　Takayasu arteritis;　clinical features;　child