Abstract: Objective To explore the clinical manifestations and endoscopic treatment of duodenal duplication in children. Method The clinical data of duodenal duplication in a child was analyzed retrospectively. Result A 13 -year-old boy presented with recurrent abdominal pain for 4 years. Blood amylase and lipase were elevated, and abdominal CT showed cystic mass, so the child was diagnosed with duodenal duplication. After endoscopic fenestration treatment, the child’s abdominal pain disappeared, and the incision healed well at the six-month follow-up. Conclusion Duodenal duplication is a rare malformation of the digestive tract. Under certain conditions, endoscopic fenestration can be the first choice for treatment.

Key words: duodenal duplication; endoscopic therapy; child