Journal of Clinical Pediatrics ›› 2021, Vol. 39 ›› Issue (9): 715-.doi: 10.3969/j.issn.1000-3606.2021.09.018

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Progress in treatment of childhood acute myeloid leukemia

WU Jun1 , ZHANG Leping2   

  1. 1 .Department of Pediatrics, Peking University Shougang Hospital, Beijing 100144 , China; 2 .Department of Pediatrics, People’s Hospital, Peking University, Beijing 100144, China
  • Online:2021-09-15 Published:2021-09-03

Abstract: Acute myeloid leukemia (AML) is a malignant clonal disease in which abnormal bone marrow hematopoietic precursor cells accumulate due to differentiation disorder and excessive proliferation of the hematopoietic stem cells. In recent years, with the rational application of risk stratification, continuous research and development of the targeted drugs, advancement of supportive treatments and maturity of the hematopoietic stem cell transplantation technology, the survival rate of pediatric AML has been significantly improved. This article reviews the progress in the treatment of pediatric AML.

Key words: acute myeloid leukemia; therapy; research advance; child