分泌性中耳炎婴幼儿气导短纯音听性脑干反应阈分析

doi:10.12372/jcp.2025.25e0793

Abstract

Abstract:

Objective To analyze the air-conduction click (c-ABR) and tone burst auditory brainstem response (Tb-ABR) thresholds in infants and young children with otitis media with effusion (OME) and explore the clinical significance of air-conduction Tb-ABR thresholds in frequency-specific hearing assessment for OME infants and young children. Methods A retrospective analysis was conducted on the ABR threshold test results of OME infants and young children aged 0~24 months and normal control infants from January 2018 to December 2022. The air-conduction click, Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz ABR thresholds were compared between the two groups. The correlation between c-ABR and Tb-ABR thresholds within the OME group was analyzed. Results The OME group consisted of 43 patients (28 boys and 15 girls), with a median age of 8 (3-14) months. The following testing was completed: air-conduction click for 43 cases (60 ears), Tb-500 Hz for 32 cases (45 ears), Tb-1000 Hz for 27 cases (39 ears), Tb-2000 Hz for 11 cases (17 ears), and Tb-4000 Hz for 11 cases (17 ears). The control group included 21 patients (10 boys and 11 girls), with a median age of 6 (4-8.25) months. The following tests were completed for the control group: air-conduction click, Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz for 21 cases (42 ears). The air-conduction click and Tb-ABR thresholds at Tb-500 Hz, Tb-1000 Hz, Tb-2000 Hz, and Tb-4000 Hz in the OME group were all significantly higher than those in the normal control group (P<0.01). In the OME group, the air-conduction c-ABR threshold was lower than the thresholds for Tb-ABR at all four frequencies (P<0.05). A positive correlation was found between the thresholds at different frequencies (P<0.05), and the correlation coefficient between Tb-2000 Hz and Tb-4000 Hz was 0.925. Conclusions Infants and young children with OME may experience hearing loss across a range of frequencies, from low to high. Compared to air-conduction c-ABR, Tb-ABR thresholds provide more information about frequency-specific hearing. In clinical settings with limited testing time, Tb-2000 Hz or Tb-4000 Hz might be selected for threshold testing, in addition to 500 Hz and 1000 Hz.

Key words: otitis media with effusion, auditory brainstem response threshold, infants and young children

CLC Number:

WANG Wei, WANG Lu, SHEN Jiali, MA Xiaobao, HE Kuan, SONG Jiayue, CHEN Jianyong, YANG Jun, JIN Yulian. Air-conduction tone burst auditory brainstem response thresholds in infants and young children with otitis media with effusion[J].Journal of Clinical Pediatrics, 2025, 43(12): 902-907.

Figures/Tables 2

References 16

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测试项目	OME组		正常组		Z值	P
测试项目	耳数	ABR反应阈	耳数	ABR反应阈	Z值	P
c-ABR	60	35(25~45)	42	10(8.75~15)	8.09	<0.001
Tb-500 Hz	45	55(45~67.5)¹⁾	42	35(30~40)	6.68	<0.001
Tb-1000 Hz	39	45(40~60)¹⁾	42	25(20~30)	6.68	<0.001
Tb-2000 Hz	17	55(42.5~60)¹⁾	42	15(10~16.25)	6.06	<0.001
Tb-4000 Hz	17	50(40~60)¹⁾	42	10(5~20)	5.98	<0.001
H值	47.20		－
P	<0.001		－

项目	r_s
项目	c-ABR	Tb-500 Hz	Tb-1000 Hz	Tb-2000 Hz	Tb-4000 Hz
c-ABR	－	0.696	0.692	0.928	0.864
Tb-500 Hz	－	－	0.877	0.781	0.728
Tb-1000 Hz	－	－	－	0.684	0.666
Tb-2000 Hz	－	－	－	－	0.925
Tb-4000 Hz	－	－	－	－	－

Air-conduction tone burst auditory brainstem response thresholds in infants and young children with otitis media with effusion

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