Journal of Clinical Pediatrics ›› 2023, Vol. 41 ›› Issue (6): 475-479.doi: 10.12372/jcp.2023.22e0327

• Literature Review • Previous Articles    

Advances in studies on risk factors and predictors of patent hemodynamically significant ductus arteriosus in premature infants

Reviewer: ZHAO Caiyan, SUN Xuan, Reviser: CHEN Ling   

  1. Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China
  • Received:2022-03-05 Online:2023-06-15 Published:2023-06-12

Abstract:

Objective Patent ductus arteriosus (PDA) is a common complication in premature infants. When it progresses to PDA with significant hemodynamics (hsPDA), it can seriously affect neonatal outcomes. Recent studies have found that some perinatal factors, platelet-related parameters, brain natriuretic peptide and ultrasound indicators can predict the occurrence of hsPDA and form an artificial intelligence prediction model. However, some predictors are still controversial, and further research is needed to build a sensitive, accurate and easy-to-use prediction model for targeted treatment of high-risk children to improve the prognosis of premature babies.

Key words: patent ductus arteriosus, risk factor, predictor, premature infant