低场强MRI在儿科和产前胎儿诊断领域中的应用

doi:10.12372/jcp.2025.24e1182

Abstract

Abstract:

Generally, the higher the magnetic field strength of a magnetic resonance imaging (MRI) scanner, the greater the likelihood of achieving a higher signal-to-noise ratio and improved image resolution within a shorter scanning time. However, high-field-strength MRI systems are associated with significant limitations, including high acquisition costs, stringent installation requirements, and substantial maintenance expenditures, which collectively hinder their widespread adoption. In contrast, low-field-strength MRI scanners, due to their relatively lower costs and enhanced portability, have increasingly been integrated into clinical practice and related research settings. This review aims to summarize the current diagnostic applications of low-field-strength MRI in pediatric neurological disorders, neonatal intensive care, and prenatal fetal imaging, while also discussing their future potential. This article seeks to provide a comprehensive overview of the clinical value and developmental trajectory of low-field-strength MRI in fetal and pediatric diagnosis.

Key words: magnetic resonance imaging, fetus, prenatal diagnosis, child

CLC Number:

DONG Suzhen, CHEN Hao, ZHANG Zhiyong, JIANG Fan. Applications of low field MRI in pediatrics and prenatal fetal diagnosis[J].Journal of Clinical Pediatrics, 2025, 43(9): 710-715.

Figures/Tables 4

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References 33

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序列名称	扫描参数	扫描时间/min
快速自旋回波T1加权成像	重复时间(TR)，1 500 ms；回波时间(TE)，6 ms；反转时间(TI)，300 ms；分辨率 1.5 mm×1.5 mm×5 mm；36层	4:52
快速自旋回波T2加权成像	TR，2 200 ms；TE，253 ms；分辨率1.5 mm×1.5 mm×5 mm；36层	5:54
T2加权液体反转恢复成像	TR，4 000 ms；TE，228 ms；TI，1 400 ms；分辨率1.6 mm×1.6 mm×5 mm；36层	9:00
弥散加权成像	TR，1 000 ms；TE，100 ms；b=0,800 s/mm²；分辨率2.4 mm×2.4 mm×6 mm；30层	9:27

序列名称	扫描参数	扫描时间/s
快速自旋回波序列	TR，98 ms；TE，180 ms；FOV 350 mm×350 mm；Matrix 224×224；分辨率1.6 mm×1.6 mm×3 mm；30层	1:00
平衡稳态自由进动序列	TR，6.02 ms；TE, 3.01 ms；FOV 350 mm×350 mm；Matrix 192×192；分辨率1.8 mm×1.8 mm×3 mm；30层	0.45
实时电影序列	TR，570 ms；TE，1.82 ms；FOV 350 mm×350 mm；Matrix 128×128；分辨率2.8 mm×2.8 mm×10 mm；1层	0.6/层
快速T1加权成像	TR，113 ms；TE，2.43 ms；FOV 295 mm×350 mm；Matrix 138×192；分辨率1.8 mm×1.8 mm×4 mm；20层	16
弥散加权成像	TR，2 500 ms；TE，74 ms；FOV 294 mm×330 mm；Matrix 82×92；分辨率3.6 mm×3.6 mm×4 mm；20层；b=0,700 s/mm²；	30

Applications of low field MRI in pediatrics and prenatal fetal diagnosis

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