Abstract: Objective　To analyze the prevalence and risk factors of extrauterine growth retardation (EUGR) in preterm infants. Methods　The clinical data from 184 preterm infants admitted from August 2014 to December 2014 were retrospectively analyzed. The intrauterine growth retardation (IUGR) and EUGR were evaluated by Fenton premature infants’ growth curve. Results　IUGR was more likely to be developed to EUGR than non-IUGR. At corrected gestational age of 40 weeks and 44 weeks, there were significant differences between EUGR and non-EUGR groups in birth weight, duration of hospitalization, duration of parenteral feeding, the gestational age at which the level of intrauterine growth was restored, the incidence of pregnancy hypertension syndrome of mother, and infant gender (P<0.05). Logistic regression analysis found that the gestational age at which the level of intrauterine growth was restored was the independent risk factor of EUGR in different stages of preterm infants. At corrected gestational age of 40 weeks, birth weight was the independent protective factor of EUGR and IUGR was the risk factor of EUGR. Conclusions　Multiple factors are involved in the development of EUGR in preterm infants. The EUGR in post neonatal are mainly related with perinatal factors, birth weight, and the nutrition during hospitalization.