Abstract: 　Objectives　To improve the knowledge in the treatment of neonatal paroxysmal supraventricular tachycardia (PSVT) with transesophageal atrial pacing (TEAP). Methods Clinical data of 24 newborns with PSVT treated with TEAP were analyzed retrospectively. Results A total of 24 term PSVT newborns (14 males and 10 females) with an ave-rage age of (8.46±8.28) d (15 h~28 d) were enrolled in this study. Successful conversion to sinus rhythms after using TEAP once was seen in 11 cases, in 5 cases after using TEAP twice, and in 3 cases after using TEAP three times; atrial fibrillation occurred in one case after 2nd TEAP and successful conversion to sinus rhythms finally occurred after using TEAP twice more; TEAP had no effect in four cases. Between PSVT newborns having successful conversion after using TEPA once and other PSVT newborns, there were no differences in incidences of birth asphyxia, respiratory or digestive infection, sepsis, congenital heart diseases, myocarditis, hypocalcemia, hyponatremia, abnormal myocardial enzymes, abnormal heart shadow on chest X-ray, recurrence rate of PSVT, and heart rate, blood pressure and hospitalization time. Conclusions TEPA is an effective treatment for neonatal PSVT.