临床儿科杂志 ›› 2014, Vol. 32 ›› Issue (1): 85-87.

• 专家笔谈 • 上一篇    下一篇

神经干细胞移植治疗重度脑瘫患儿的研究进展

周菊花方素珍周细中综述李, 宏审校   

  1. 南方医科大学珠江医院儿科中心 (广东广州 510282)
  • 收稿日期:2014-01-15 出版日期:2014-01-15 发布日期:2014-01-15

Research progress of neural stem cell transplantation in the treatment of severe cerebral palsy in child Reviewer: ZHOU Juhua, FANG Suzhen, ZHOU Xizhong, Reviser: LI Hong (Department of Pediatrics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong, China)

  • Received:2014-01-15 Online:2014-01-15 Published:2014-01-15

摘要:

 脑性瘫痪(CP)是儿科神经系统常见疾病中致残率最高的疾病之一。轻至中度患儿以综合康复治疗为主,重度患儿则见效慢且疗效不明显。干细胞移植为该病带来了全新的治疗方法,目前正处于广泛的研究中,基础实验和临床研究均取得了一些有意义的成果,但目前国内还处于起步阶段,临床应用开展较少,文章就儿童重度脑瘫的神经干细胞(NSCs)治疗最新进展作一综述。

Abstract:  Cerebral palsy (CP) is one of the most common diseases of the nervous system leading to developmental disabi-lity. Comprehensive rehabilitation is still the main treatment in children with mild to moderate CP, but it has limited effects for children with severe CP. Stem cell transplantation is a new treatment for this disease which has obtained some meaningful results based on extensive studies including basic experiments and clinical researches. Currently, stem cell transplantation is still in its infancy, subject to many restrictions in the clinical application. This review will summarize the research progress of stem cell transplantation in children with severe cerebral palsy in recent years.