临床儿科杂志 ›› 2014, Vol. 32 ›› Issue (1): 83-84.

• 专家笔谈 • 上一篇    下一篇

胸腺基质淋巴细胞生成素与变态反应性疾病的关系

张春霞1 陈柏谕2 综述   

  1. 1. 内蒙古医科大学附属医院儿科(内蒙古呼和浩特 010050);
    2. 内蒙古医科大学研究生学院(内蒙古呼和浩特 010059)
  • 收稿日期:2014-01-15 出版日期:2014-01-15 发布日期:2014-01-15

Relationship between thymic stromal lymphopoietin and allergic diseases Reviewer: ZHANG Chunxia1, CHEN Baiyu2 (1.Department of Pediatric, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, Inner Mongolia, China; 2.Graduate School, Inner Mongolia Medical University, Hohhot 010059, Inner Mongolia, China)

  • Received:2014-01-15 Online:2014-01-15 Published:2014-01-15

摘要:

 胸腺基质淋巴细胞生成素(TSLP)是由上皮细胞衍生的一类白介素7样细胞因子,于1994年由Friend等学者首次发现并报道。此后越来越多的研究表明,其广泛出现在变态反应性疾病中,在变态反应性疾病的发病机制中扮演重要角色。文章对近年来TSLP及其与变态反应性疾病密切相关性的研究进展作一综述。

Abstract:  Thymic stromal lymphopoietin (TSLP) is a type of interleukin 7-like cytokine which was reported by Friend for the first time in 1994. Since then, an increasing number of researches have showed that TSLP exists and plays potential pathoge-nic role in the allergic diseases. In this review, the recent progress in the relationship between TSLP and allergic diseases was summarized.