关键词: 川崎病；　休克；　冠状动脉损害

Abstract: Objective　To explore the clinical characteristics of Kawasaki disease shock syndrome (KDSS). Method The clinical data of hospitalized children diagnosed with KDSS between June 2014 and October 2017 were retrospectively analyzed. The children diagnosed with Kawasaki disease (KD) at the same time with stable hemodynamics were selected as controls. The clinical characteristics of the two groups of children were analyzed and compared. Results　Compared with 119 KD children, 21 KDSS children had higher percentage of cervical lymph node enlargement and incomplete KD, higher levels of neutrophils, C-reactive protein, D-dimer and N-terminal brain natriuretic peptide precursor, lower platelet count and lower serum albumin level; children with KDSS were more likely to have no response to the first dose of gamma globulin, to suffer from coronary artery damage and to have longer total fever course and hospitalization time than children with KD. The differences were statistically significant (P<0.05). Conclusion　Children with KDSS have more intense inflammatory reaction, more obvious hypercoagulability, and are prone to gamma globulin resistance

Key words: 　Kawasaki disease;　shock;　coronary lesion