临床儿科杂志 ›› 2020, Vol. 38 ›› Issue (3): 205-.doi: 10.3969/j.issn.1000-3606.2020.03.011

• 综合报道 • 上一篇    下一篇

儿童大动脉炎1 例报告

张月甥 1, 李峻峰 2, 鄢素琪 1, 汤建桥 1, 吴智 1, 李红 1, 周俪姗 1, 张林利 1, 熊小丽 1, 李建军 3   

  1. 1.华中科技大学同济医学院附属武汉儿童医院中西医结合科(湖北武汉 430016);2.青岛妇女儿童医院 中医科(山东青岛 266034);3.华中科技大学同济医学院附属武汉同济医院放射科(湖北武汉 430030)
  • 发布日期:2020-04-07
  • 通讯作者: 熊小丽 电子信箱:3112897691@qq.com
  • 基金资助:
    2016年度黄鹤英才(医疗卫生)计划项目[No. 武人才办(2017)2号]

Takayasu’s arteritis in children: a case report

 ZHANG Yuesheng1, LI Junfeng2, YAN Suqi1, TANG Jianqiao1, WU Zhi1, LI Hong1, ZHOU Lishan1, Zhang Linli1, XIONG Xiaoli1, LI Jianjun3   

  1. 1.Department of Integrative Chinese and Westerm Medicine, Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430016, Hubei, China; 2.Traditional Chinese Medicine Department, Qingdao Women and Children’s Hospital, Qingdao 266034, Shandong, China; 3. Depratment of Radiology, Tongji Hospital of Tongji Medical College, Huanzhong University of Science and Technology, Wuhan 430030, Hubei, China
  • Published:2020-04-07

摘要:  目的 探讨儿童多发性动脉炎发作的临床特点。方法 分析1例最终确诊为大动脉炎患儿的临床资料,并复 习相关文献。结果 7岁女性患儿,反复不明原因发热,炎症指标均明显升高,抗感染治疗无效。行正电子发射计算机断层 显像(PET-CT)考虑血管炎。给予糖皮质激素治疗后,病情出现反复,行血管造影明确大动脉炎诊断。随后予手术、糖皮质 激素及环磷酰胺联合治疗,未再复发。结论 对于不明原因发热,伴炎症指标升高而抗感染治疗无效者,需警惕多发性动 脉炎;早期行PET-CT,确诊后使用糖皮质激素及环磷酰胺联合治疗可有效改善预后。

关键词:  多发性动脉炎; 发热; 正电子发射计算机断层显像; 儿童

Abstract: Objective To explore the clinical characteristics of Takayasu’s arteritis in children. Method The clinical data of Takayasu’s arteritis in a child were analyzed, and the relevant literatures were reviewed. Results The 7-year-old girl had recurrent fever of unknown causes, and the inflammatory indicators were significantly increased, and the anti-infection treatment was ineffective. PET-CT was performed and vasculitis was considered. After receiving glucocorticoid therapy, the patient's condition was recurrent, and angiography was performed to confirm the diagnosis of arteritis. Subsequently, the patient had surgical operation, and treated with glucocorticoids and cyclophosphamide, and no recurrence occurred. Conclusions For those with unexplained fever, accompanied by elevated inflammatory indicators and ineffective anti-infective treatment, clinician should be alert to the possibility of Takayasu’s arteritis. Early PET-CT examination and treatment by combination of glucocorticoid and cyclophosphamide after diagnosis can effectively improve the prognosis.

Key words:  Takayasu’s arteritis; fever; PET-CT; child