临床儿科杂志 ›› 2021, Vol. 39 ›› Issue (12): 941-.doi: 10.3969/j.issn.1000-3606.2021.12.014

• 综合报道 • 上一篇    下一篇

儿童肺曼氏裂头蚴病1 例报告

徐言文, 蔡康, 李华君, 徐姗姗, 杜惠敏, 俞慧菊, 黄丽素   

  1. 上海交通大学医学院附属新华医院 新华儿童医院感染科(上海 200092)
  • 发布日期:2021-12-22
  • 基金资助:
    黄丽素 电子信箱:huanglisu@xinhuamed.com.cn

Pulmonary sparganosis in children: a case report and literature review

w XU Yanwen, CAI Kang, LI Huajun, XU Shanshan, DU Huimin, YU Huiju, HUANG Lisu   

  1. Department of Infectious Disease, Xinhua Children's Hospital, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092 , China
  • Published:2021-12-22

摘要: 目的 探讨儿童肺曼氏裂头蚴病的临床特征及诊疗方法。方法 回顾1例确诊为肺曼氏裂头蚴病患儿的临 床资料。结果 患儿,女,13岁。咳嗽20天伴胸闷、活动后气促,抗感染治疗无效。胸部CT示胸腔积液和右肺中叶巨大空 洞,内见特殊的寄生虫虫体影。通过基因二代测序确诊为肺曼氏裂头蚴病。患儿予手术联合吡喹酮驱虫治疗后恢复出院, 随访中未见异常。结论 肺曼氏裂头蚴病临床少见。详细的流行病学史询问、血清常规寄生虫抗体筛查、肺部CT检查有 助于早期诊断,诊断困难时可进一步作病理活检及基因测序。

关键词: 肺曼氏裂头蚴病; 胸腔积液; 肺部空洞

Abstract: Objective To investigate the clinical manifestations, diagnosis and treatment of pulmonary sparganosis in children. Methods The clinical data of pulmonary sparganosis in a child were retrospectively analyzed. Results A 13 -year-old girl presented with cough for twenty days, concomitantly with chest discomfort and shortness of breath after activities. Anti-infective therapy was ineffective. Pulmonary imaging showed pleural effusion and a large cavity in the middle lobe of the right lung with a distinctive parasite body shadow. The diagnosis of pulmonary sparganosis was confirmed by the next-generation sequencing. The patient was discharged after surgery combined with praziquantel deinsectization, and no abnormality was observed during follow-up. Conclusion Pulmonary sparganosis is a clinically rare condition. For patients suspected of having lung parasitic infection, detailed inquiry of epidemiological history, screening of routine serum parasite antibodies and pulmonary CT examination should be done for early diagnosis. Further, pathological biopsy and gene sequencing can be performed when the diagnosis is still unclear.

Key words: pulmonary sparganosis; pleural effusion; pulmonary cavitie