苏州地区下呼吸道感染住院患儿卡他莫拉菌感染与气候因素相关性研究

临床儿科杂志 ›› 2014, Vol. 32 ›› Issue (6): 524-527.

苏州地区下呼吸道感染住院患儿卡他莫拉菌感染与气候因素相关性研究

孙慧明，周卫芳，季伟，严永东，陈正荣，陶云珍

苏州大学附属儿童医院呼吸科（江苏苏州　215003）

收稿日期:2014-01-14 出版日期:2014-06-15 发布日期:2014-06-15

The relationship between meteorological parameters and the prevalence of Moraxella catarrhalis infection in children hospitalized with acute respiratory infection in Suzhou　

SUN Huiming, ZHOU Weifang, JI Wei, YAN Yongdong, CHEN Zhengrong, TAO Yunzheng

(Department of Respiratory Disease, Children's Hospital Affiliated to Soochow University, Suzhou 215003, Jiangsu, China)

Received:2014-01-14 Published:2014-06-15 Online:2014-06-15

摘要/Abstract

摘要：

　目的　探讨苏州地区住院患儿急性呼吸道卡他莫拉菌感染与气候因素的相关性。方法　2006年1月至2010年12月连续60个月对因急性下呼吸道感染而住院的8143例患儿进行下呼吸道细菌病原学监测。卡他莫拉菌的分离鉴定采用常规培养法，同时收集同期苏州地区月平均气温、月平均湿度、月总雨量、月总日照时间、月平均风速等气象资料。采用季节分解法、Spearman秩相关和多元逐步回归法分析卡他莫拉菌感染与气候因素的相关性。结果　卡他莫拉菌感染率为4.04%。苏州地区急性下呼吸道卡他莫拉菌感染好发于冬春季。卡他莫拉菌的月感染率与月平均气温、月平均风速、日照时间均呈负相关。经多元逐步回归分析，仅风速对卡他莫拉菌检出率的影响有统计学意义（β=-0.023，P=0.001）。结论　卡他莫拉菌是苏州地区儿童急性下呼吸道感染的重要病原之一，其流行特点与气候因素关系密切。

Abstract: 　Objective　To explore the correlation of meteorological parameters with the epidemic of acute Moraxella catarrhalis respiratory infection in hospitalized children in Suzhou. Methods A total of 8143 children with acute respiratory infection were participated in the trial during 2006 to 2010, and the secretions of nasopharynx were collected for bacterium culture. Moraxella catarrhalis was identified according to the routine technique of culture. Meteorological parameters including mean temperature, relative humidity, rainfall amount, duration of sunshine and mean wind velocity were collected monthly during the same period. The relationship between the epidemic of Moraxella catarrhalis and metrorological parameters were analyzed by seasonal decomposition method, the Spearman rank correlation and stepwise regression analysis. Results Moraxella catarrhalis was identified in 4.04% of 8 143 specimens. The prevalence of acute Moraxella catarrhalis respiratory infection was higher during winter and spring. The monthly infection rate of Moraxella catarrhalis was negatively correlated with mean temperature as well as duration of sunshine and wind velocity. Wind velocity was independent risk factor for Moraxella catarrhalis infection. Conclusions Moraxella catarrhalis is a primary pathogen in respiratory tract infection in children in Suzhou. The epidemic of Moraxella catarrhalis is closely related to meteorological parameters.

孙慧明，周卫芳，季伟，严永东，陈正荣，陶云珍. 苏州地区下呼吸道感染住院患儿卡他莫拉菌感染与气候因素相关性研究[J]. 临床儿科杂志, 2014, 32(6): 524-527.

SUN Huiming,ZHOU Weifang,JI Wei,YAN Yongdong,CHEN Zhengrong,TAO Yunzheng
. The relationship between meteorological parameters and the prevalence of Moraxella catarrhalis infection in children hospitalized with acute respiratory infection in Suzhou　[J]. , 2014, 32(6): 524-527.

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