临床儿科杂志 ›› 2021, Vol. 39 ›› Issue (4): 308-.doi: 10.3969/j.issn.1000-3606.2021.04.018

• 文献综述 • 上一篇    下一篇

支气管肺发育不良诊断标准的研究进展

李睿雯综述 史 源审校   

  1. 重庆医科大学附属儿童医院新生儿科/儿科研究所 儿童发育疾病研究教育部重点实验室 国家儿童健康与疾病临床医学研究中心 儿童发育重大疾病国家国际科技合作基地 儿科学重庆市重点实验室(重庆 400014)
  • 发布日期:2021-04-15
  • 基金资助:
    国家重点研发计划数字诊疗装备研发重点专项(No. 2018 YFC 0114405)

Research progress of diagnostic criteria for bronchopulmonary dysplasia

Reviewer: LI Ruiwen, Reviser: SHI Yuan   

  1. Department of Neonatology/Pediatric Research Institute; Ministry of Education Key Laboratory of Child Development and Disorders; National Clinical Research Center for Child Health and Disorders; China International Science and Technology Cooperation base of Child development and Critical Disorders; Chongqing Key Laboratory of Pediatrics; Children’s Hospital of Chongqing Medical University, Chongqing 400014, China
  • Published:2021-04-15

摘要: 支气管肺发育不良(BPD)是早产儿,特别是极早产儿及超早产儿中常见的呼吸系统疾病,发病率有逐年增高 趋势,且伴随多种并发症,远期预后不良。BPD诊断标准是其临床研究及诊断和治疗发展的基础。文章总结20世纪60年 代以来BPD诊断标准的变迁,着重分析并比较21世纪初以来BPD诊断及分级标准的发展,包括2001年美国国家儿童和 人类发展研究所的BPD共识,及在此基础上进行衍生的,分别于2018和2019年提出的改善后的新标准,讨论其分别的优 势及不足。总体综述BPD诊断标准的发展,以期为制定符合我国临床的BPD诊断标准提供依据。

关键词: 支气管肺发育不良; 诊断标准; 机械通气; 经鼻高流量吸氧; 远期预后

Abstract: Bronchopulmonary dysplasia (BPD) is a common respiratory disease in premature infants, especially in very preterm infants and extremely preterm infants. The incidence has been increasing year by year in trend, and it was accompanied by a variety of complications and its long-term prognosis is poor. The diagnostic criteria of BPD are the basis of its clinical research, diagnosis and treatment. This paper firstly summarizes the changes in diagnostic criteria for BPD since 1960 s, and then analyzes and compares the development of diagnostic criteria and grading criteria for BPD since the beginning of 21 st century. These criteria include the National Institute for Children and Human Development (NICHD) 2001 Consensus and the new revised standards in 2018 and 2019 which are derived from the 2001 Consensus. Finally, the advantages and disadvantages of each are discussed. In this paper, the development of diagnostic criteria for BPD is reviewed in order to provide a basis for the establishment of diagnostic criteria for BPD in accordance with clinical practice in China.

Key words: bronchopulmonary dysplasia; diagnostic criteria; mechanical ventilation; high-flow nasal cannula; long-term prognosis