肠道菌群在脓毒症中的作用和研究进展
Research progress on the role of intestinal flora in sepsis
Received date: 2022-06-13
Online published: 2023-08-10
王燕飞 , 谈林华 . 肠道菌群在脓毒症中的作用和研究进展[J]. 临床儿科杂志, 2023 , 41(8) : 634 -640 . DOI: 10.12372/jcp.2023.22e0820
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection which affects children's health. The intestinal flora play an important regulatory role in host metabolism and immunity and are associated with a variety of diseases. Studies have shown that sepsis and clinical treatments can lead to intestinal flora imbalance in children, which further affects the prognosis of the disease; while healthy intestinal flora can reduce the susceptibility of children to sepsis and improve the survival of sepsis, and ameliorate the damage to the function of organs. This article reviews the related research on intestinal flora and sepsis, in order to contribute to the prevention and treatment of sepsis in children.
Key words： sepsis; intestinal flora; metabolism; child
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