脂质代谢在哮喘中作用机制的研究进展
收稿日期: 2023-03-14
网络出版日期: 2024-05-10
基金资助
国家自然科学基金项目(81800027);辽宁省应用基础研究计划项目(2022JH2/101500004)
Research progress on mechanism of lipid metabolism in asthma
Received date: 2023-03-14
Online published: 2024-05-10
陈少甜 综述 , 杨男 审校 . 脂质代谢在哮喘中作用机制的研究进展[J]. 临床儿科杂志, 2024 , 42(5) : 461 -466 . DOI: 10.12372/jcp.2024.23e0201
Asthma is one of the most common chronic respiratory diseases, affecting all age group. Its prevalence and social healthcare costs are increasing every year. The results of numerous studies in recent years have conclusively demonstrated the role of lipid molecules as powerful signaling molecules that regulate a variety of cellular biological processes. By regulating different cells in the airways of asthma patients, they influence the occurrence and development of the disease. Therefore, this article summarizes the potential metabolic biomarkers in asthma, and explores the mechanisms of lipid metabolism in asthma pathogenesis on different cells to provide ideas for personalized asthma treatment from the lipidomics and asthma studies that have been developed in recent years.
Key words： asthma; lipid metabolism; lipidomics; fatty acids; immune cell
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