晨尿促性腺激素在中枢性性早熟诊断和监测中的应用
收稿日期: 2025-04-14
录用日期: 2025-05-12
网络出版日期: 2025-06-01
基金资助
国家自然科学基金项目(82270837);浙江省科技厅重点研发计划项目(2020C03121)
The application of morning urinary gonadotropin measurement in the diagnosis and monitoring of central precocious puberty
Received date: 2025-04-14
Accepted date: 2025-05-12
Online published: 2025-06-01
戴铖钧 , 王春林 . 晨尿促性腺激素在中枢性性早熟诊断和监测中的应用[J]. 临床儿科杂志, 2025 , 43(6) : 408 -410 . DOI: 10.12372/jcp.2025.25e0393
Central precocious puberty (CPP) significantly impacts children's growth potential and psychological well-being. Currently, the diagnosis of CPP primarily relies on the GnRH stimulation test, which is cumbersome and involves multiple blood draws, causing patient discomfort. In recent years, morning urinary gonadotropin measurement has gained attention due to its non-invasiveness and convenience. This article reviews recent advances in urinary gonadotropin testing for CPP diagnosis, analyzes its clinical feasibility, and discusses current challenges and future directions.
Key words： central precocious puberty; morning voided urinary; gonadotropin; diagnosis; monitor
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