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38例儿童颞叶难治性癫痫病理分析#br#

  • 武江 ,
  • 赵焕芬 ,
  • 毛金丽 ,
  • 王江娅 ,
  • 李文玲 ,
  • 娄燕
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  • 河北省人民医院1.儿科,2.功能神经外科,3.病理科(河北石家庄 050051)

收稿日期: 2015-03-15

  网络出版日期: 2015-03-15

Neuropathological findings in 38 children with temporal lobe intractable epilepsy

  • Wu Jiang ,
  • Zhao Huanfen ,
  • Mao Jinli ,
  • WANG Jiangya ,
  • LI Wenling ,
  • LOU Yan
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  • 1. Department of Pediatrics, 2. Department of Functional Neurosurgery,  3.Department of Pathology, Hebei General Hospital, Shijiazhuang 050051, Hebei, China

Received date: 2015-03-15

  Online published: 2015-03-15

摘要

目的 探讨儿童颞叶难治性癫痫的病理特征。方法 回顾性分析2011年10月至2013年10月行手术治疗的38例颞叶癫痫患儿的病理资料。结果 38例患儿年龄2.5~14岁,男21例、女17例。病理诊断局灶性皮层发育不良(FCD)21例,其中FCDⅠa 1例、FCDⅠb 2例、FCDⅡa 2例、FCDⅡb 3例、FCDⅢa 5例、FCDⅢb 1例、FCDⅢc 1例、FCDⅢd 6例;微皮层发育不良3例;单纯海马硬化3例;神经系统肿瘤7例,其中胚胎发育不良性神经上皮瘤5例,星形胶质瘤2例;脑炎2例;蛛网膜囊肿2例。结论 FCD是引起儿童颞叶难治性癫痫最常见的原因,其中FCDIIId型为最常见的亚型。

本文引用格式

武江 , 赵焕芬 , 毛金丽 , 王江娅 , 李文玲 , 娄燕 . 38例儿童颞叶难治性癫痫病理分析#br#[J]. 临床儿科杂志, 2015 , 33(3) : 265 . DOI: 10.3969j.issn.1000-3606.2015.03.017

Abstract

Objectives To explore the neuropathological characteristics of children with temporal intractable epilepsy. Methods A retrospective analysis of the pathological characteristics was conducted in 38 children who underwent epilepsy surgery from December 2011 to December 2013. Results Among 38 patients, aged 2.5-14 years, 21 boys and 17 girls, 21 cases had focal cortical dysplasia (FCD), 1 case had FCDⅠa, 2 cases had FCDⅠb, 1 case had FCDⅡa, 3 cases had FCDⅡb, 5 cases had CDⅢa, 1 case had FCDⅢb, 1 case had FCDⅢc, 6 cases had FCDⅢd. Three cases had microdysgenesis, 3 cases had simple hippocampal sclerosis, 7 cases had neoplasms, 5 cases had dysembryoplastic neuroepithelial tumor, 2 cases had astroglioma, 2 cases had encephalitis, 2 cases had arachnoid cyst. Conclusions FCD is the most common form that causes temporal lobe intractable epilepsy in children. FCDIIId is the most common subtype in FCD.
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