川崎病冠状动脉损伤机制免疫遗传研究进展

doi:10.12372/jcp.2023.21e1773

Abstract

Abstract:

Kawasaki disease (KD) is a kind of common diseases in children mainly characterized by systemic vasculitis. The most serious complication of KD is cardiovascular disease involving coronary arteries. Even after treatment, some children still have sequelae such as coronary aneurysms. KD has become one of the most common causes of acquired heart disease in children. At present, the pathogenesis of KD coronary artery injury is not clear. From the perspective of immunogenetics, the latest research results and progress of coronary artery injury mechanism of KD are reviewed in the article.

Key words: Kawasaki disease, coronary artery, gene, child

Reviewer: QIU Jiayun, Reviser: ZHOU Guoping. Immune genetics of coronary artery injury pathogenesis in Kawasaki disease[J].Journal of Clinical Pediatrics, 2023, 41(1): 66-72.

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Immune genetics of coronary artery injury pathogenesis in Kawasaki disease

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