Journal of Clinical Pediatrics ›› 2024, Vol. 42 ›› Issue (9): 811-816.doi: 10.12372/jcp.2024.23e0892

• Literature Review • Previous Articles     Next Articles

Research progress of central nervous system injury associated with pediatric acute lymphoblastic leukemia and its treatment

Reviewer: CHU Sijia1,2, Reviser: TANG Jihong1   

  1. 1. Department of Neurology, Children’s Hospital of Soochow University, Suzhou 215025, Jiangsu, China
    2. Department of Child Healthcare, Kunshan Bailu Community Health Service Center, Suzhou 215300, Jiangsu, China
  • Received:2023-09-12 Online:2024-09-15 Published:2024-09-04

Abstract:

Acute lymphoblastic leukemia (ALL) is the most common malignancy in children, and its central nervous system complications significantly impact the prognosis of children. In addition to the brain damage caused by ALL itself, recent researches have shown that anti-tumor therapy may also result in adverse effects. Investigating central nervous system injury associated with anti-tumor therapy in children with ALL is crucial for early identification and intervention of complications, ultimately leading to improved prognosis and quality of life for children.

Key words: central nervous system injury, acute lymphoblastic leukemia, injury mechanism, child