CAR-T细胞治疗在儿童中的毒副作用

doi:10.12372/jcp.2024.22e1605

Abstract

Abstract:

Chimeric antigen receptor (CAR)-T cells have become one of the most promising methods for the treatment of malignant tumors due to their specific recognition function and cytotoxicity. However, it also has a series of side effects, especially in children. Toxic reactions can develop rapidly and endanger life in severe cases. In this paper, the side effects of CAR-T cell therapy in children, as well as its clinical manifestations and treatment are summarized, aiming to optimize its application in children.

Key words: chimeric antigen receptor T cell, side effect, child

YIN Mengmeng, HU Qun. Side effects of CAR-T cell therapy in children[J].Journal of Clinical Pediatrics, 2024, 42(4): 361-366.

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Side effects of CAR-T cell therapy in children

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