›› 2015, Vol. 33 ›› Issue (3): 238-.doi: 10.3969j.issn.1000-3606.2015.03.010

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Relationship between autoimmune thyroid disorders and thyroid cancer in children

ZHANG Ling1, LI Shuhong1, ZHANG Jing1,  XU Guochun   

  1. Affiliated Hospital of Hubei Institute for Nationalities, Enshi 445000, Hubei, China
  • Received:2015-03-15 Online:2015-03-15 Published:2015-03-15

Abstract: Objective To investigate the relationship between autoimmune thyroid disorders (AITD) and thyroid cancer (TC) in children. Methods  Clinical date from 68 patients who underwent thyroidectomy and were histologically confirmed with TC were retrospectively analyzed from 2000 to 2008. Age, gender, nodular size, lymph node metastasis, and invasive status of thyroid cancer were compared between patients with and without AITD. Results  In 68 patients with TC, 45.6% (31/68) patients had concurrent AITD. Compared with those without AITD, a greater female preponderance, older age, smaller tumour size, higher TSH values, higher TG  values, shorter survival time, lower disease free survival rate, and higher relapse rate were found in patients with AITD (P<0.05). Conclusions  AITD are associated with TC in children. Follow-up is suggested in children with AITD.