›› 2015, Vol. 33 ›› Issue (3): 265-.doi: 10.3969j.issn.1000-3606.2015.03.017

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Neuropathological findings in 38 children with temporal lobe intractable epilepsy

WANG Jiangya1, LI Wenling2, Wu Jiang2, Zhao Huanfen3, Mao Jinli1, LOU Yan1   

  1. 1. Department of Pediatrics, 2. Department of Functional Neurosurgery,  3.Department of Pathology, Hebei General Hospital, Shijiazhuang 050051, Hebei, China
  • Received:2015-03-15 Online:2015-03-15 Published:2015-03-15

Abstract: Objectives To explore the neuropathological characteristics of children with temporal intractable epilepsy. Methods A retrospective analysis of the pathological characteristics was conducted in 38 children who underwent epilepsy surgery from December 2011 to December 2013. Results Among 38 patients, aged 2.5-14 years, 21 boys and 17 girls, 21 cases had focal cortical dysplasia (FCD), 1 case had FCDⅠa, 2 cases had FCDⅠb, 1 case had FCDⅡa, 3 cases had FCDⅡb, 5 cases had CDⅢa, 1 case had FCDⅢb, 1 case had FCDⅢc, 6 cases had FCDⅢd. Three cases had microdysgenesis, 3 cases had simple hippocampal sclerosis, 7 cases had neoplasms, 5 cases had dysembryoplastic neuroepithelial tumor, 2 cases had astroglioma, 2 cases had encephalitis, 2 cases had arachnoid cyst. Conclusions FCD is the most common form that causes temporal lobe intractable epilepsy in children. FCDIIId is the most common subtype in FCD.