Abstract: Objective　To explore hemodynamics response to the graded exercise test in overweight and normal weight teenagers. Methods A total of 87 overweight teenagers were enrolled and divided into girl overweight group (GO, n=20), girl normal weight group (GN, n=21), boy overweigh group (BO, n=25) and boy normal weight group (BN, n=21). The following variables were measured: anthropometrics (weight, height and BMI), hemodynamic variables at rest and during graded exercise test such as rest systolic blood pressure (SBP), diastolic blood pressure (DBP), mean aterial pressure (MAP) and heart rate (HR) as well as maximal SBP, DBP, MAP and HR. Results The rest SBP in BO group was higher than that in BN group (P<0.01). During graded exercise test, compared with GN group, maximal SBP were significantly higher while maximal oxygen uptake (VO2max) were significantly lower in GO group (P<0.05). Furthermore, compared with BN group, maximal SBP were significantly higher while VO2max were significantly lower in BO group (P<0.01). When height, weight, BMI, and VO2max were adjusted as confounding factors, the difference in SBP was not significant between GO and GN groups (P=0.105) while the differences in rest SBP and maximal SBP were still significant between BO and BN groups (P=0.021, P=0.016). Conclusions Arterial blood pressure was higher in overweight teenagers than that in normal weight teenagers both at rest and during graded exercise test. Influence of overweight on hemodynamic parameters was more obvious in male teenagers in comparison with female teenagers.