Abstract: 　Objectives　To evaluate the quality of global clinical practice guidelines for children with urinary tract infection (UTI) and provide reference for the development of the clinical guidelines for Chinese children with UTI. Methods　The Medline, Embase, National Guideline Clearinghouse (NGC), guidelines international network (GIN ), national Institute for Health and Clinical Excellence (NICE), Wanfang database, Chinese national knowledge infrastructure (CNKI), Chinese practice guideline network (CPGN, from inception to January 2015 ), and related English and Chinese websites were searched. The published guidelines for children with UTI were screened according to the inclusion and elimination criteria. AGREE was used to evaluate the methodological quality of the guidelines. The consistency among the assessors was evaluated by correlation coefficient (ICC). Results　A total of 10 guidelines for children with UTI were included, covering 9 continents and 4 organizations. The published time was from 1999 to 2015, including 7 articles in headed version and 3 articles in updated version. The topics of these guidelines were diagnosis, management, prevention, risk assessment and treatment , and were all evidence-based. The AGREE II score of included guidelines showed that the average scores on six domains were 88%, 57%, 54%, 98%, 26% and 44% respectively. The scores in the field of scope, purpose, and clarity in 7 guidelines were > 50%. The scores of guidelines published by National Institute for Health and Clinical Excellence (NICE) of United Kingdom and Aragon Institute of Health Sciences (IACS) were all >50% in six areas. Conclusions　The quality of clinical guidelines for children with UTI in different countries and regions varied greatly. Evidence-based is the trend in the development of clinical practice guidelines. The rigorous methodology, report standardization and practicability of guidelines should be emphasized.