Abstract:  To explore the physical growth in infants with eczema who treated with regular use of glucocorticoid. Methods A total of 115 full-term infants newly diagnosed with eczema were included in this study and treated with topical glucocorticoids regularly. The severity of eczema was assessed and anthropometric indices were measured regularly. Results Both weight for age (WAZ) and length for age (LAZ) at birth and 6-month-old were higher than those of World Health Organization (WHO) child growth standards. However, the LAZ at diagnosis and 3 months after treatment were lower than that of WHO child growth standards. The weight, length, and the growth rate from birth to the time of diagnosis were all lower than those of WHO child growth standards. While the growth rate after treatment for 3 to 6 months was higher than that of WHO child growth standards. The increases of WAZ and LAZ were significantly different among three periods: at birth to diagnose, at diagnosis to 3 months after treatment, and 3 months to 6 months after treatment (P<0.001). Conclusion In the early stage of eczema, the growth rate was decreased when the symptoms were not controlled. However, after treatment, the growth rate was increased. It is suggested that treatment of regular topical glucocorticoids has no adverse effects on growth of eczema infants, and also is beneficial to the catch-up growth of infants.