生长激素与肠道菌群相关性研究进展

doi:10.12372/jcp.2022.21e1593

Abstract

Abstract:

Human growth hormone (hGH), synthesized by eosinophils in the anterior pituitary gland, exerts effects on growth and metabolism through insulin-like growth factor-1 (IGF-1). Short stature caused by GH deficiency or insufficient secretion is called growth hormone deficiency (GHD), but its specific etiology and exact mechanism have not been fully explained. In recent years, with the in-depth understanding and research of gut microbiota, it has been found that the GH-IGF-1 axis is correlated with gut microbiota. This article reviews the research on the relationship between the GH-IGF-1 axis and the gut microbiota.

Key words: growth hormone, short stature, growth hormone deficiency, gut microbiota, child

SHI Liyun, WANG Aiping. Research progress on the correlation between growth hormone and gut microbiota[J].Journal of Clinical Pediatrics, 2022, 40(12): 955-959.

References 36

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Research progress on the correlation between growth hormone and gut microbiota

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