Journal of Clinical Pediatrics ›› 2024, Vol. 42 ›› Issue (8): 737-740.doi: 10.12372/jcp.2024.23e0251

• Literature Review • Previous Articles     Next Articles

Progress of Clinical Research on IgA Vasculitis in Children

Reviewer:CHAI Yahui, YANG Dasheng, ZHANG He, Reviser: BI Lingyun   

  1. The First Affiliated Hospital of Xinxiang Medical University, Weihui 453100, Heinan, China
  • Received:2023-03-28 Online:2024-08-15 Published:2024-08-06

Abstract:

IgA vasculitis (IgAV) is an autoimmune disease caused by IgA deposition in small blood vessels. It is characterized by non-thrombocytopenic purpura, abdominal pain, joint swelling and pain, hematuria or proteinuria. The disease is self-limited, with only a minority progressing to end-stage renal disease in later life. This paper reviews the clinical features of IgAV in children and the mechanisms of renal involvement, and discusses the treatment and prognosis of the disease.

Key words: IgA vasculitis, Henoch-Schönlein purpura, purpura nephritis, child